This study sought to determine the significant relationship between the impact of the covid-19 pandemic on college students’ emotional and mental reactions. It also aims to explore the emotional and mental challenges brought on by the covid-19 pandemic in the lives of college students, specifically in the Davao de Oro State College-New Bataan Branch. This study utilized mixed methods parallel convergent design. In the Quantitative study, 86 respondents completed an online questionnaire assessing variables perceived threats related to COVID-19. Statistical analyses included Pearson correlations. At the same time, the Qualitative study was conducted in-depth-interview with eight informants. The quantitative findings showed a significant relationship between the impacts of the covid-19 pandemic influencing students’ emotional and mental reactions. The result is in line with the statement of Cao W et al. (2020) these stressors were positively associated with the level of negative psychological symptoms experienced during the pandemic. It is noted that emotions can hinder students in their academics, commitment, and their success in school since emotional aspects affect the way they learn. Seven major themes emerged from the qualitative study: 1) Lonely and stressed 2) Stress 3) Anxiety and Depression 4) Communicate to Family 5) Talk to friends 6) Think Positive 7) Communication is essential. Change of learning modality, students to faced stress, anxiety, and depression. In contrast, Communication with family and friends and manifesting positivity play a significant role in dealing with students’ emotional and mental reactions. Social support from family and friends enables students to deal with the problematic situations brought about by the pandemic.